Microhomology-assisted scarless genome editing in human iPSCs

Kim, SI; Matsumoto, T; Kagawa, H; Nakamura, M; Hirohata, R; Ueno, A; Ohishi, M; Sakuma, T; Soga, T; Yamamoto, T; Woltjen, K

Woltjen, K (reprint author), Kyoto Univ, Ctr iPS Cell Res & Applicat CiRA, Kyoto 6068507, Japan.; Woltjen, K (reprint author), Kyoto Univ, Hakubi Ctr Adv Res, Kyoto 6068501, Japan.

NATURE COMMUNICATIONS, 2018; 9 ():

Abstract

Gene-edited induced pluripotent stem cells (iPSCs) provide relevant isogenic human disease models in patient-specific or healthy genetic backgrounds. ......

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