Chalcones: As Potent alpha-amylase Enzyme Inhibitors; Synthesis, In Vitro, and In Silico Studies

Ali, M; Khan, M; Zaman, K; Wadood, A; Iqbal, M; Alam, A; Shah, SA; Rehman, AU; Yousaf, M; Rafique, R; Khan, KM

Khan, KM (corresponding author), Univ Karachi, Int Ctr Chem & Biol Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan.; Khan, KM (corresponding author), Imam Abdulrahman Bin Faisal Univ, Inst Res & Med Consultat IRMC, Dept Clin Pharm, POB 1982, Dammam 31441, Saudi Arabia.

MEDICINAL CHEMISTRY, 2021; 17 (8): 903

Abstract

Background: The inhibition of alpha-amylase enzyme is one of the best therapeutic approach for the management of type II diabetes mellitus. Chalcone p......

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