期刊: MEDICINAL CHEMISTRY, 2021; 17 (9)
Background: Schisandronic acid (SA), a triterpenoid from fruits of Schisandra sphenanthera, inhibited pan-genotypic HCV entry into human hepatocytes b......
期刊: MEDICINAL CHEMISTRY, 2021; 17 (9)
Background: Reactive oxygen species are involved in the etiology and progress of many kinds of diseases such as cancer, cardiovascular diseases, infla......
期刊: MEDICINAL CHEMISTRY, 2021; 17 (9)
Background: Thiourea is a classical urease inhibitor which is usually used as a positive control, and many N,N'-disubstituted thioureas have been dete......
期刊: MEDICINAL CHEMISTRY, 2021; 17 (6)
Background: As a target for anticancer treatment, aminopeptidase N (APN) shows its overexpression on diverse malignant tumor cells and associates with......
期刊: MEDICINAL CHEMISTRY, 2021; 17 (8)
Background: The inhibition of alpha-amylase enzyme is one of the best therapeutic approach for the management of type II diabetes mellitus. Chalcone p......
期刊: MEDICINAL CHEMISTRY, 2021; 17 (2)
Background: Some species of Cordyceps sensu lato are famous Chinese herbs with significant biological activities, often used as edible food and tradit......
期刊: MEDICINAL CHEMISTRY, 2021; 17 (8)
Background: Arylnaphthalene lignan lactones are a class of natural products containing the phenyl-naphthyl skeleton. Some arylnaphthalene lignan lacto......
期刊: MEDICINAL CHEMISTRY, 2021; 17 (3)
Background: ATP-binding cassette Super-family G member 2 protein is an active ATP-binding cassette transporter with the potential to combat cancer ste......
期刊: MEDICINAL CHEMISTRY, 2021; 17 (1)
Purpose: Carbon monoxide-releasing molecules (CORMs) are a special class of organometallic complexes that have been reported to offer beneficial effec......
期刊: MEDICINAL CHEMISTRY, 2021; 17 (4)
Background: HIV-1 protease inhibitor (PIs) is a good choice for AIDS patients. Nevertheless, for PIs, there are several bugs in clinical application, ......
期刊: MEDICINAL CHEMISTRY, 2021; 17 (5)
Background: 'FufangKushen injection' was a Chinese Traditional anticancer drug, which has been widely used to treat cancer in combination with other a......
期刊: MEDICINAL CHEMISTRY, 2020; 16 (5)
Background: Observational studies support the inflammation hypothesis in coronary heart disease (CHD). As a pleiotropic proinflammatory cytokine, Inte......
期刊: MEDICINAL CHEMISTRY, 2020; 16 (1)
Background: Topiroxostat is an excellent xanthine oxidase (XO) inhibitor, possessing a specific 3,5-diaryl-1,2,4-triazole framework. Objective: The pr......
期刊: MEDICINAL CHEMISTRY, 2020; 16 (1)
Objective: Due to the incidence of resistance, a series of sulfonamide-derived 1,2,4-triazoles were synthesized and evaluated. Method: The novel sulfo......
期刊: MEDICINAL CHEMISTRY, 2020; 16 (3)
Background : In the past century, many phenazines were isolated from the marine microorganism, and some of these phenazines possessed potent antibacte......