Empagliflozin Attenuates Myocardial Sodium and Calcium Dysregulation and Reverses Cardiac Remodeling in Streptozotocin-Induced Diabetic Rats

Lee, TI; Chen, YC; Lin, YK; Chung, CC; Lu, YY; Kao, YH; Chen, YJ

Chen, YJ (reprint author), Taipei Med Univ, Wan Fang Hosp, Cardiovasc Res Ctr, Taipei 11696, Taiwan.; Chen, YJ (reprint author), Taipei Med Univ, Coll Med, Grad Inst Clin Med, Taipei 11031, Taiwan.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019; 20 (7):

Abstract

Diabetes mellitus (DM) has significant effects on cardiac calcium (Ca2+) and sodium (Na+) regulation. Clinical studies have shown that empagliflozin (......

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