CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells

Giese, APJ; Tang, YQ; Sinha, GP; Bowl, MR; Goldring, AC; Parker, A; Freeman, MJ; Brown, SDM; Riazuddin, S; Fettiplace, R; Schafer, WR; Frolenkov, GI; Ahmed, ZM

Ahmed, ZM (reprint author), Univ Maryland, Sch Med, Dept Otorhinolaryngol Head & Neck Surg, Baltimore, MD 21201 USA.; Frolenkov, GI (reprint author), Univ Kentucky, Dept Physiol, Coll Med, Lexington, KY 40536 USA.

NATURE COMMUNICATIONS, 2017; 8 ( ):

Abstract

Inner ear hair cells detect sound through deflection of stereocilia, the microvilli-like projections that are arranged in rows of graded heights. Calc......

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