m(6)A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade

Yang, S; Wei, JB; Cui, YH; Parka, G; Shah, P; Deng, Y; Aplin, AE; Lu, ZK; Hwang, S; He, C; He, YY

He, YY (reprint author), Univ Chicago, Dept Med, Sect Dermatol, 5841 S Maryland Ave, Chicago, IL 60637 USA.; He, C (reprint author), Univ Chicago, Dept Chem, Dept Biochem & Mol Biol, Inst Biophys Dynam, 5735 S Ellis Ave, Chicago, IL 60637 USA.; He, C (rep

NATURE COMMUNICATIONS, 2019; 10 ():

Abstract

Melanoma is one of the most deadly and therapy-resistant cancers. Here we show that N-6-methyladenosine (m(6)A) mRNA demethylation by fat mass and obe......

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