High risk genetic variants of human insulin receptor substrate 1(IRS1) infer structural instability and functional interference

Bhattacharjee, A; Pranto, SMA; Ahammad, I; Chowdhury, ZM; Juliana, FM; Das, KC; Keya, CA; Salimullah, M

Chowdhury, ZM (通讯作者)，Natl Inst Biotechnol, Bioinformat Div, Dhaka 1349, Bangladesh.;Salimullah, M (通讯作者)，Natl Inst Biotechnol, Mol Biotechnol Div, Dhaka 1349, Bangladesh.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023; 41 (24): 15150

Abstract

Insulin receptor substrate 1(IRS1) is a signaling adapter protein encoded by the IRS1 gene. This protein delivers signals from insulin and insulin-lik......

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