Intradermal vaccination of live attenuated influenza vaccine protects mice against homologous and heterologous influenza challenges

Lee, ACY; Zhang, ANJX; Li, C; Chen, YX; Liu, FF; Zhao, Y; Chu, H; Fong, CHY; Wang, P; Lau, SY; To, KKW; Chen, HL; Yuen, KY

Yuen, KY (corresponding author), Univ Hong Kong, Li Ka Shing Fac Med, Dept Microbiol, Hong Kong, Peoples R China.; Yuen, KY (corresponding author), Univ Hong Kong, Res Ctr Infect & Immunol, Hong Kong, Peoples R China.; Yuen, KY (corresponding author), Univ Hong Kong, State Key Lab Emerging Infect Dis, Hong Kong, Peoples R China.

NPJ VACCINES, 2021; 6 (1):

Abstract

We previously developed a temperature-sensitive, and NS1 gene deleted live attenuated influenza vaccine (DelNS1-LAIV) and demonstrated its potent prot......

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