A novel patient-derived orthotopic xenograft (PDOX) mouse model of highly-aggressive liver metastasis for identification of candidate effective drug-combinations

Zhang, ZY; Hu, KW; Miyake, K; Kiyuna, T; Oshiro, H; Wangsiricharoen, S; Kawaguchi, K; Higuchi, T; Razmjooei, S; Miyake, M; Chawla, SP; Singh, SR; Hoffman, RM

Hoffman, RM (corresponding author), AntiCanc Inc, San Diego, CA 92111 USA.; Hoffman, RM (corresponding author), Univ Calif San Diego, Dept Surg, San Diego, CA 92103 USA.; Hu, KW (corresponding author), Beijing Univ Chinese Med, Dongfang Hosp, Dept Oncol, Beijing, Peoples R China.; Singh, SR (corresponding author), NCI, Basic Res Lab, Frederick, MD 21701 USA.

SCIENTIFIC REPORTS, 2020; 10 (1):

Abstract

Liver metastasis is a recalcitrant disease that usually leads to death of the patient. The present study established a unique patient-derived orthotop......

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