Targeting aerobic glycolysis by dichloroacetate improves Newcastle disease virus-mediated viro-immunotherapy in hepatocellular carcinoma

Meng, G; Li, BH; Chen, AX; Zheng, MH; Xu, TC; Zhang, HL; Dong, J; Wu, JH; Yu, DC; Wei, JW

Yu, DC (corresponding author), Nanjing Univ, Sch Med, Affiliated Drum Tower Hosp, Dept Hepatobiliary Surg, Nanjing 210008, Peoples R China.; Wei, JW (corresponding author), Nanjing Univ, Sch Med, Jiangsu Key Lab Mol Med, Nanjing 210093, Peoples R China.

BRITISH JOURNAL OF CANCER, 2020; 122 (1): 111

Abstract

Background Oncolytic viro-immunotherapy holds promise for cancer treatment. While immune activation can be robustly triggered by oncolytic viruses, ne......

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