TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease

Zhang, ZY; Harischandra, DS; Wang, R; Ghaisas, S; Zhao, JY; McMonagle, TP; Zhu, GX; Lacuarta, KD; Song, J; Trojanowski, JQ; Xu, H; Lee, VMY; Yang, XL

Yang, XL (通讯作者)，Univ Penn, Perelman Sch Med, Dept Canc Biol & Abramson Family Canc Res Inst, Philadelphia, PA 19104 USA.

SCIENCE, 2023; 381 (6656): 413

Abstract

Aggregation of tau into filamentous inclusions underlies Alzheimer's disease (AD) and numerous other neurodegenerative tauopathies. The pathogenesis o......

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