Neuroendocrine lineage commitment of small cell lung cancers can be leveraged into p53-independent non-cytotoxic therapy

Biswas, S; Kang, K; Ng, KP; Radivoyevitch, T; Schalper, K; Zhang, H; Lindner, DJ; Thomas, A; Macpherson, D; Gastman, B; Schrump, DS; Wong, KK; Velcheti, V; Saunthararajah, Y

Saunthararajah, Y (通讯作者)，Cleveland Clin, Taussig Canc Inst, Dept Translat Hematol & Oncol Res, Cleveland, OH 44195 USA.;Velcheti, V (通讯作者)，NYU, Langone Laura & Isaac Perlmutter Canc Ctr, Thorac Oncol Program, New York, NY 10016 USA.;Saunthararajah, Y (通讯作者)，Cleveland Clin, Taussig Canc Inst, Dept Radiat Oncol, Cleveland Hts, OH 44195 USA.

CELL REPORTS, 2023; 42 (8):

Abstract

Small cell lung cancers (SCLCs) rapidly resist cytotoxic chemotherapy and immune checkpoint inhibitor (ICI) treatments. New, non-cross-resistant thera......

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