Activation of spinal PDGFR beta in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats

Jia, XQ; Zhang, AQ; Li, Z; Peng, XL; Tian, XB; Gao, F

Gao, F (corresponding author), Huazhong Univ Sci & Technol, Tongji Hosp, Dept Anesthesiol, Tongji Med Coll, 1095 Jiefang Ave, Wuhan 430030, Peoples R China.

JOURNAL OF NEUROCHEMISTRY, 2021; 158 (2): 373

Abstract

The adverse side effects of opioids, especially antinociceptive tolerance, limit their clinical application. A recent study reported that platelet-der......

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