Developing a dual VEGF/PDL1 inhibitor based on high-affinity scFv heterodimers as an anti-cancer therapeutic strategy

Tzuri, N; Yegodayev, KM; Novoplansky, O; Elkabets, M; Aharoni, A; Papo, N

Papo, N (通讯作者)，Ben Gurion Univ Negev, Avram & Stella Goldstein Goren Dept Biotechnol Eng, IL-8410501 Beer Sheva, Israel.;Papo, N (通讯作者)，Ben Gurion Univ Negev, Natl Inst Biotechnol Negev, IL-8410501 Beer Sheva, Israel.

SCIENTIFIC REPORTS, 2023; 13 (1):

Abstract

Cancer progression is enhanced by the interaction of programmed death-ligand 1 (PDL1), which is associated with inhibition of the immune response agai......

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