Methylation of KRAS by SETD7 promotes KRAS degradation in non-small cell lung cancer

Chiang, CY; Fan, SQ; Zheng, HM; Guo, WJ; Zheng, ZH; Sun, YH; Zhong, CQ; Zeng, J; Li, SH; Zhang, M; Xiao, T; Zheng, D

Xiao, T; Zheng, D (通讯作者),Shenzhen Univ, Med Sch, Thorac Surg Dept, Int Canc Ctr,Guangdong Key Lab Genome Instabil & H, Shenzhen 518055, Peoples R China.

CELL REPORTS, 2023; 42 (9):

Abstract

Oncogenic KRAS mutations are a key driver for initiation and progression in non-small cell lung cancer (NSCLC). However, how post-translational modifi......

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