An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zone

Lee, EHY; Lee, EA; Kong, EJ; Chon, H; Llaiqui-Condori, M; Park, CH; Park, BY; Kang, NR; Yoo, JS; Lee, HS; Kim, HS; Park, SH; Choi, SW; Vestweber, D; Lee, JH; Kim, P; Lee, WS; Kim, I

Kim, I (通讯作者),Korea Adv Inst Sci & Technol KAIST, Grad Sch Med Sci & Engn, Daejeon 34141, South Korea.;Lee, WS (通讯作者),PharmAbcine Inc, R&D Ctr, Daejeon 34047, South Korea.;Kim, I (通讯作者),Korea Adv Inst Sci & Technol, Biomed Res Ctr, Daejeon 34141, South Korea.

EXPERIMENTAL AND MOLECULAR MEDICINE, 2023; 55 (2): 470

Abstract

Brain tumours: antibody blocks blood vessel abnormalityAn antibody targeting key signalling pathways could prevent brain tumor vessels from being abno......

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