Human amniotic mesenchymal stem cells-derived IGFBP-3, DKK-3, and DKK-1 attenuate liver fibrosis through inhibiting hepatic stellate cell activation by blocking Wnt/beta-catenin signaling pathway in mice

Liu, QW; Ying, YM; Zhou, JX; Zhang, WJ; Liu, ZX; Jia, BB; Gu, HC; Zhao, CY; Guan, XH; Deng, KY; Xin, HB

Deng, KY; Xin, HB (通讯作者)，Nanchang Univ, Natl Engn Res Ctr Bioengn Drugs & Technol, Inst Translat Med, 1299 Xuefu Rd, Nanchang 330031, Jiangxi, Peoples R China.;Deng, KY; Xin, HB (通讯作者)，Nanchang Univ, Sch Life & Sci, Nanchang 330031, Jiangxi, Peoples R China.

STEM CELL RESEARCH & THERAPY, 2022; 13 (1):

Abstract

Background: Liver fibrosis is an outcome of restoring process in chronic liver injury. Human amniotic mesenchymal stem cells (hAMSCs) derived from amn......

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