UNC93B1 curbs cytosolic DNA signaling by promoting STING degradation

He, ZL; Ye, SC; Xing, YF; Jiu, YM; Zhong, J

Zhong, J (corresponding author), Chinese Acad Sci, Inst Pasteur Shanghai, Unit Viral Hepatitis, CAS Key Lab Mol Virol & Immunol, Shanghai, Peoples R China.; Zhong, J (corresponding author), Univ Chinese Acad Sci, Beijing, Peoples R China.

EUROPEAN JOURNAL OF IMMUNOLOGY, 2021; 51 (7): 1672

Abstract

UNC93B1 is a trafficking chaperone of endosomal Toll-like receptors (TLRs) and plays an essential role in the TLR-mediated innate signaling. However, ......

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