Synthesis of benzoxazole-based vorinostat analogs and their antiproliferative activity

Mantzourani, C; Gkikas, D; Kokotos, A; Nummela, P; Theodoropoulou, MA; Wu, KC; Fairlie, DP; Politis, PK; Ristimaki, A; Kokotos, G

Kokotos, G (corresponding author), Natl & Kapodistrian Univ Athens, Dept Chem, Athens 15771, Greece.; Kokotos, G (corresponding author), Natl & Kapodistrian Univ Athens, Ctr Excellence Drug Design & Discovery, Athens 15771, Greece.

BIOORGANIC CHEMISTRY, 2021; 114 ():

Abstract

Hydroxamic acid derivatives constitute an interesting novel class of antitumor agents. Three of them, including vorinostat, are approved drugs for the......

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