Enhanced expression of beta cell Ca(v)3.1 channels impairs insulin release and glucose homeostasis

Yu, J; Shi, Y; Zhao, KX; Yang, G; Yu, LN; Li, YX; Andersson, EM; Ammala, C; Yang, SN; Berggren, PO

Yu, J; Yang, SN; Berggren, PO (corresponding author), Karolinska Inst, Rolf Luft Res Ctr Diabet & Endocrinol, SE-17176 Stockholm, Sweden.; Yang, SN (corresponding author), Northeast Normal Univ, Natl Engn Lab Druggable Gene & Prot Screening, Changchun 130024, Peoples R China.; Berggren, PO (corresponding author), Sichuan Univ, West China Hosp, Dept Endocrinol & Metab, Chengdu 610041, Peoples R China.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1): 448

Abstract

Voltage-gated calcium 3.1 (Ca(v)3.1) channels are absent in healthy mouse beta cells and mediate minor T-type Ca2+ currents in healthy rat and human b......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索