The ubiquitin E3 ligase TRIM10 promotes STING aggregation and activation in the Golgi apparatus

Kong, LL; Sui, C; Chen, T; Zhang, L; Zhao, W; Zheng, Y; Liu, BY; Cheng, XC; Gao, CJ

Cheng, XC; Gao, CJ (通讯作者)，Shandong Univ, Key Lab Infect & Immun Shandong Prov, Jinan 250012, Shandong, Peoples R China.;Cheng, XC; Gao, CJ (通讯作者)，Shandong Univ, Sch Biomed Sci, Dept Immunol, Jinan 250012, Shandong, Peoples R China.

CELL REPORTS, 2023; 42 (4):

Abstract

STING is an endoplasmic reticulum-resident protein regulating innate immunity. After binding with cyclic guanosine monophosphate-AMP (cGAMP), STING tr......

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