A CTLA-4 Antagonizing DNA Aptamer with Antitumor Effect

Huang, BT; Lai, WY; Chang, YC; Wang, JW; Yeh, SD; Lin, EPY; Yang, PC

Lin, EPY (reprint author), Natl Taiwan Univ Hosp, Dept Med Res, Natl Ctr Excellence Clin Trials, Taipei, Taiwan.; Lin, EPY (reprint author), Natl Taiwan Univ Hosp, Dept Med Res, Res Ctr, Taipei, Taiwan.; Yang, PC (reprint author), Natl Taiwan Univ Hosp, D

MOLECULAR THERAPY-NUCLEIC ACIDS, 2017; 8 ( ): 520

Abstract

The successful translation of cytotoxic T lymphocyte antigen-4 (CTLA-4) blockade has revolutionized the concept of cancer immunotherapy. Although mono......

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