Mitochondrial ROS-induced ERK1/2 activation and HSF2-mediated AT(1)R upregulation are required for doxorubicin-induced cardiotoxicity

Huang, CY; Chen, JY; Kuo, CH; Pai, PY; Ho, TJ; Chen, TS; Tsai, FJ; Padma, VV; Kuo, WW; Huang, CY

Huang, CY (reprint author), China Med Univ, Grad Inst Basic Med Sci, China Med Univ Hosp, Taichung 40402, Taiwan.

JOURNAL OF CELLULAR PHYSIOLOGY, 2018; 233 (1): 463

Abstract

Doxorubicin (DOX), one useful chemotherapeutic agent, is limited in clinical use because of its serious cardiotoxicity. Growing evidence suggests that......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索