HMG-CoA Reductase Inhibitors as Drug Leads against Naegleria fowleri

Hahn, HJ; Abagyan, R; Podust, LM; Roy, S; Ali, IKM; Debnath, A

Debnath, A (corresponding author), Univ Calif San Diego, Skaggs Sch Pharm & Pharmaceut Sci, Ctr Discovery & Innovat Parasit Dis, La Jolla, CA 92093 USA.

ACS CHEMICAL NEUROSCIENCE, 2020; 11 (19): 3089

Abstract

Primary amebic meningoencephalitis (PAM), caused by the free-living ameba Naegleria fowleri, has a fatality rate of over 97%. Treatment of PAM relies ......

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