A common CORIN variant in hypertension reduces corin intracellular trafficking by exposing an inhibitory N-terminus

He, ML; Zhang, Y; Li, H; Liu, M; Dong, NZ; Wu, QY

Wu, QY (corresponding author), Cleveland Clin, Cleveland, OH 44195 USA.; Dong, NZ (corresponding author), Soochow Univ, Cyrus Tang Hematol Ctr, Suzhou 215123, Peoples R China.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020; 530 (1): 35

Abstract

Corin is a transmembrane serine protease that activates atrial natriuretic peptide, a cardiac hormone essential for normal blood pressure. Corin is sy......

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