Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine

Trinh, MN; Brown, MS; Goldstein, JL; Han, J; Vale, G; McDonald, JG; Seemann, J; Mendell, JT; Lu, FR

Brown, MS; Goldstein, JL (corresponding author), Univ Texas Southwestern Med Ctr Dallas, Dept Mol Genet, Dallas, TX 75390 USA.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (31): 18521

Abstract

Animal cells acquire cholesterol from receptor-mediated uptake of low-density lipoprotein (LDL), which releases cholesterol in lysosomes. The choleste......

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