Expanding the Therapeutic Window of EGFR-Targeted PE24 Immunotoxin for EGFR-Overexpressing Cancers by Tailoring the EGFR Binding Affinity

Jun, SY; Kim, DS; Kim, YS

Kim, YS (通讯作者),Ajou Univ, Dept Mol Sci & Technol, Suwon 16499, South Korea.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022; 23 (24):

Abstract

Immunotoxins (ITs), which are toxin-fused tumor antigen-specific antibody chimeric proteins, have been developed to selectively kill targeted cancer c......

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