The Fab fragment of anti-IgE C epsilon 2 domain prevents allergic reactions through interacting with IgE-Fc epsilon RI alpha complex on rat mast cells

Hirano, T; Koyanagi, A; Kotoshiba, K; Shinkai, Y; Kasai, M; Ando, T; Kaitani, A; Okumura, K; Kitaura, J

Hirano, T (reprint author), Juntendo Univ, Div Hematol, Dept Gen Med, Dept Internal Med,Nerima Hosp,Nerima Ku, 3-1-10 Nerima, Tokyo, Japan.

SCIENTIFIC REPORTS, 2018; 8 ():

Abstract

Immunoglobulin E (IgE) plays a central role in the pathogenesis of Type I hypersensitivity through interaction with a high-affinity receptor (Fc epsil......

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