C/EBP beta promotes poly(ADP-ribose) polymerase inhibitor resistance by enhancing homologous recombination repair in high-grade serous ovarian cancer

Tan, JH; Zheng, X; Li, MC; Ye, F; Song, CY; Xu, C; Zhang, XX; Li, WQ; Wang, Y; Zeng, SQ; Li, HY; Chen, G; Huang, XY; Ma, D; Liu, D; Gao, QL

Liu, D; Gao, QL (corresponding author), Huazhong Univ Sci & Technol, Tongji Med Coll, Canc Biol Res Ctr, Key Lab,Minist Educ,Tongji Hosp, Wuhan, Peoples R China.; Liu, D; Gao, QL (corresponding author), Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Dept Obstet & Gynecol, Wuhan, Peoples R China.

ONCOGENE, 2021; 40 (22): 3845

Abstract

PARP inhibitors (PARPi) are efficacious in treating high-grade serous ovarian cancer (HG-SOC) with homologous recombination (HR) deficiency. However, ......

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