Quantitative Visualization of the Interaction between Complement Component C1 and Immunoglobulin G: The Effect of C(H)1 Domain Deletion

Yanaka, S; Nishiguchi, S; Yogo, R; Watanabe, H; Shen, JA; Yagi, H; Uchihashi, T; Kato, K

Uchihashi, T; Kato, K (通讯作者)，Natl Inst Nat Sci, Inst Mol Sci IMS, Exploratory Res Ctr Life & Living Syst ExCELLS, 5-1 Higashiyama, Okazaki, Aichi 4448787, Japan.;Kato, K (通讯作者)，Nagoya City Univ, Fac & Grad Sch Pharmaceut Sci, Mizuho Ku, 3-1 Tanabe Dori, Nagoya, Aichi 4678603, Japan.;Uchihashi, T (通讯作者)，Nagoya Univ, Dept Phys, Chikusa Ku, Furo Cho, Nagoya, Aichi 4648602, Japan.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022; 23 (4):

Abstract

Immunoglobulin G (IgG) adopts a modular multidomain structure that mediates antigen recognition and effector functions, such as complement-dependent c......

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