Reversine exhibits antineoplastic activity in JAK2(V)(617)(F)-positive myeloproliferative neoplasms

Lima, K; Carlos, JAEG; Alves-Paiva, RD; Vicari, HP; Santos, FPD; Hamerschlak, N; Costa-Lotufo, LV; Traina, F; Machado-Neto, JA

Machado-Neto, JA (reprint author), Univ Sao Paulo, Biomed Sci Inst, Dept Pharmacol, Sao Paulo, Brazil.

SCIENTIFIC REPORTS, 2019; 9 ():

Abstract

JAK2/STAT signaling participates in the Ph-negative myeloproliferative neoplasms (MPN) pathophysiology and has been targeted by ruxolitinib, a JAK1/2 ......

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