Orally Absorbed Cyclic Peptides

Nielsen, DS; Shepherd, NE; Xu, WJ; Lucke, AJ; Stoermer, MJ; Fairlie, DP

Stoermer, MJ; Fairlie, DP (reprint author), Univ Queensland, Inst Mol Biosci, Div Chem & Struct Biol, Brisbane, Qld 4072, Australia.; Fairlie, DP (reprint author), Univ Queensland, Australian Res Council, Inst Mol Biosci, Ctr Excellence Adv Mol Imaging, B

CHEMICAL REVIEWS, 2017; 117 (12): 8094

Abstract

Peptides and proteins are not orally bioavailable in mammals, although a few peptides are intestinally absorbed in small amounts. Polypeptides are gen......

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