FXYD3 functionally demarcates an ancestral breast cancer stem cell subpopulation with features of drug-tolerant persisters

Li, MJ; Nishimura, T; Takeuchi, Y; Hongu, T; Wang, YM; Shiokawa, D; Wang, K; Hirose, H; Sasahara, A; Yano, M; Ishikawa, S; Inokuchi, M; Ota, T; Tanabe, M; Tada, KI; Akiyama, T; Cheng, X; Liu, CC; Yamashita, T; Sugano, S; Uchida, Y; Chiba, T; Asahara, H; Nakagawa, M; Sato, S; Miyagi, Y; Shimamura, T; Nagai, LAE; Kanai, A; Katoh, M; Nomura, S; Nakato, R; Suzuki, Y; Tojo, A; Voon, DC; Ogawa, S; Okamoto, K; Foukakis, T; Gotoh, N

Gotoh, N (通讯作者)，Kanazawa Univ, Canc Res Inst, Inst Frontier Sci Initiat, Div Canc Cell Biol, Kakuma machi, 9201192 Kanazawa, Japan.

JOURNAL OF CLINICAL INVESTIGATION, 2023; 133 (22):

Abstract

The heterogeneity of cancer stem cells (CSCs) within tumors presents a challenge in therapeutic targeting. To decipher the cellular plasticity that fu......

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