Safety, Tolerability, Pharmacokinetics, Target Occupancy, and Concentration-QT Analysis of the Novel BTK Inhibitor Evobrutinib in Healthy Volunteers

Becker, A; Martin, EC; Mitchell, DY; Grenningloh, R; Bender, AT; Laurent, J; Mackenzie, H; Johne, A

Becker, A (reprint author), Merck KGaA, Darmstadt, Germany.

CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 0; ():

Abstract

Bruton's tyrosine kinase (BTK) is a key regulator of B cell receptor and Fc receptor signaling, and a rational therapeutic target for autoimmune disea......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索