A Highly Sensitive FRET Biosensor for AMPK Exhibits Heterogeneous AMPK Responses among Cells and Organs

Konagaya, Y; Terai, K; Hirao, Y; Takakura, K; Imajo, M; Kamioka, Y; Sasaoka, N; Kakizuka, A; Sumiyama, K; Asano, T; Matsuda, M

Terai, K (reprint author), Kyoto Univ, Grad Sch Biostudies, Lab Bioimaging & Cell Signaling, Kyoto 6068501, Japan.

CELL REPORTS, 2017; 21 (9): 2628

Abstract

AMP-activated protein kinase (AMPK), a master regulator of cellular metabolism, is a potential target for type 2 diabetes. Although extensive in vitro......

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