Co-Targeting PIM Kinase and PI3K/mTOR in NSCLC

Moore, G; Lightner, C; Elbai, S; Brady, L; Nicholson, S; Ryan, R; O'Sullivan, KE; O'Byrne, KJ; Blanco-Aparicio, C; Cuffe, S; O'Neill, M; Heavey, S; Finn, SP; Gately, K

Gately, K (corresponding author), St James Hosp, Trinity Translat Med Inst, Dept Clin Med, Dublin, Ireland.

CANCERS, 2021; 13 (9):

Abstract

Simple Summary PIM kinases interact with major oncogenic players, including the PI3K/Akt pathway, and provide an escape mechanism leading to drug resi......

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