Stereoselective Solvolysis in the Synthesis of Dorzolamide Intermediates

Martinelli, A; Volpicelli, R; Verzini, M; Cotarca, L; Maini, L; Pengo, P; Pasquato, L

Pengo, P; Pasquato, L (通讯作者)，Univ Trieste, Dept Chem & Pharmaceut Sci, I-34127 Trieste, Italy.;Cotarca, L (通讯作者)，ZaCh Syst, Res & Dev Labs, I-36045 Vicenza, Italy.

ACS OMEGA, 2023; 8 (31): 28851

Abstract

The key intermediate in the synthesis of dorzolamide,(4S,6S)-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol-7,7-dioxide,can beobtained in the diast......

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