Targeting Myocardial Mitochondria- STING-Polyamine Axis Prevents Cardiac Hypertrophy in Chronic Kidney Disease

Han, WH; Du, CH; Zhu, YG; Ran, L; Wang, Y; Xiong, JC; Wu, YD; Lan, QG; Wang, YQ; Wang, LT; Wang, JP; Yang, K; Zhao, JH

Yang, K; Zhao, JH (通讯作者)，Third Military Medical Univ, Army Med Univ, Key Lab Prevent & Treatment Chron Kidney Dis Chong, Chongqing Clinical Res Ctr Kidney & Urol Dis,Xinqi, Chongqing, Peoples R China.;Yang, K; Zhao, JH (通讯作者)，Army Med Univ, Xinqiao Hosp, Dept Nephrol, Xinqiao Rd, Chongqing 400037, Peoples R China.

JACC-BASIC TO TRANSLATIONAL SCIENCE, 2022; 7 (8): 820

Abstract

Chronic kidney disease (CKD) is well recognized as a distinct contributor to cardiac hypertrophy, while the un-derlying mechanism remains incompletely......

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