Assessing Scaffold Diversity of Kinase Inhibitors Using Alternative Scaffold Concepts and Estimating the Scaffold Hopping Potential for Different Kinases

Dimova, D; Bajorath, J

Bajorath, J (reprint author), Rheinische Friedrich Wilhelms Univ, LIMES Program Unit Chem Biol & Med Chem, Dept Life Sci Informat, B IT, Dahlmannstr 2, D-53113 Bonn, Germany.

MOLECULES, 2017; 22 (5):

Abstract

Publicly available kinase inhibitors provide a large source of information for structure-activity relationship analysis and kinase drug design. In thi......

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