Vaccinia-related kinase 2 drives pancreatic cancer progression by protecting Plk1 from Chfr-mediated degradation

Zhu, HQ; Li, Q; Zhao, YL; Peng, H; Guo, LY; Zhu, J; Jiang, Z; Zeng, ZX; Xu, B; Chen, SS

Xu, B (corresponding author), Nanchang Univ, Dept Burns, Affiliated Hosp 1, Nanchang, Jiangxi, Peoples R China.; Chen, SS (corresponding author), Nanchang Univ, Dept Neurol, Affiliated Hosp 2, Nanchang, Jiangxi, Peoples R China.

ONCOGENE, 2021; 40 (28): 4663

Abstract

As a key cell cycle regulator, polo-like kinase 1 (Plk1) has been recognized as a crucial factor involved in the progression of pancreatic cancer (PC)......

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