Vanillin downregulates NNMT and attenuates NNMT-related resistance to 5-fluorouracil via ROS-induced cell apoptosis in colorectal cancer cells-MedSci.cn

Vanillin downregulates NNMT and attenuates NNMT-related resistance to 5-fluorouracil via ROS-induced cell apoptosis in colorectal cancer cells

Li, GL; Kong, BB; Tong, QC; Li, YJ; Chen, LF; Zeng, J; Yu, HT; Xie, XY; Zhang, J

Zhang, J (corresponding author), Zhejiang Univ, Sir Run Run Shaw Hosp, Sch Med, Dept Clin Lab, 3 East Qingchun Rd, Hangzhou 310016, Zhejiang, Peoples R China.

ONCOLOGY REPORTS, 2021; 45 (6):

Abstract

Chemoresistance is the main cause of poor prognosis in colorectal cancer (CRC). Nicotinamide N-methyltransferase (NNMT) is a metabolic enzyme that is ......

Full Text Link