Induction of COX-2 by feline calicivirus via activation of the MEK1-ERK1/2 pathway, and attenuation of feline lung inflammation and injury by MEK1 inhibitor AZD6244 (selumetinib)

Liu, Y; Shi, WD; Xie, QQ; Wang, JG; Gu, CC; Ji, ZH; Xiao, J; Liu, WQ

Liu, WQ (通讯作者)，China Agr Univ, Coll Biol Sci, Dept Biochem & Mol Biol, State Key Lab Agrobiotechnol, 2 Yuanmingyuan West Rd, Beijing 100193, Peoples R China.;Xiao, J (通讯作者)，Chinese Peoples Liberat Army Gen Hosp, Eight Med Ctr, Dept Geriatr, Beijing, Peoples R China.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022; 604 (): 8

Abstract

Feline calicivirus (FCV) is an important and highly prevalent pathogen of cats that causes acute infectious respiratory disease. Here it is shown in v......

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