Deficiency in Dipeptidyl Peptidase-4 Promotes Chemoresistance Through the CXCL12/CXCR4/mTOR/TGF beta Signaling Pathway in Breast Cancer Cells

Li, SL; Fan, Y; Kumagai, A; Kawakita, E; Kitada, M; Kanasaki, K; Koya, D

Kanasaki, K; Koya, D (corresponding author), Kanazawa Med Univ, Dept Diabetol & Endocrinol, Uchinada, Ishikawa 9200293, Japan.; Kanasaki, K; Koya, D (corresponding author), Kanazawa Med Univ, Med Res Inst, Div Anticipatory Mol Food Sci & Technol, Uchinada, Ishikawa 9200293, Japan.; Kanasaki, K (corresponding author), Shimane Univ, Internal Med 1, Fac Med, 89-1 Enya Cho, Izumo, Shimane 6938501, Japan.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020; 21 (3):

Abstract

Dipeptidyl peptidase (DPP)-4, a molecular target of DPP-4 inhibitors, which are type 2 diabetes drugs, is expressed in a variety of cell types, tissue......

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