Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19

Le, BL; Andreoletti, G; Oskotsky, T; Vallejo-Gracia, A; Rosales, R; Yu, K; Kosti, I; Leon, KE; Bunis, DG; Li, C; Kumar, GR; White, KM; Garcia-Sastre, A; Ott, M; Sirota, M

Sirota, M (corresponding author), UCSF, Dept Pediat, San Francisco, CA 94143 USA.; Sirota, M (corresponding author), UCSF, Bakar Computat Hlth Sci Inst, San Francisco, CA 94143 USA.

SCIENTIFIC REPORTS, 2021; 11 (1):

Abstract

The novel SARS-CoV-2 virus emerged in December 2019 and has few effective treatments. We applied a computational drug repositioning pipeline to SARS-C......

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