Design, synthesis and anti-diabetic activity of triazolotriazine derivatives as dipeptidyl peptidase-4 (DPP-4) inhibitors

Patel, BD; Bhadada, SV; Ghate, MD

Ghate, MD (reprint author), Nirma Univ, Inst Pharm, Dept Pharmaceut Chem, SG Highway, Ahmadabad 382481, Gujarat, India.

BIOORGANIC CHEMISTRY, 2017; 72 ( ): 345

Abstract

Type 2 diabetes mellitus (T2DM) is one of the major global metabolic disorders characterized by insulin resistance and chronic hyperglycemia. Inhibiti......

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