Discovery of new small molecule inhibitors of the BPTF bromodomain

Liang, XC; Cao, Y; Duan, Z; Wang, MC; Zhang, NX; Ding, YL; Luo, C; Lu, N; Chen, SJ

Lu, N (通讯作者)，China Pharmaceut Univ, Dept Physiol, State Key Lab Nat Med, Jiangsu Key Lab Carcinogenesis & Intervent,Sch Bas, Nanjing 210009, Peoples R China.;Chen, SJ (通讯作者)，Chinese Acad Sci, Shanghai Inst Mat Med, Ctr Chem Biol, State Key Lab Drug Res,Drug Discovery & Design Ctr, Shanghai 201203, Peoples R China.;Chen, SJ (通讯作者)，Univ Chinese Acad Sci, Beijing 100049, Peoples R China.

BIOORGANIC CHEMISTRY, 2023; 134 ():

Abstract

Chromatin remodeling regulates many basic cellular processes, such as gene transcription, DNA repair, and programmed cell death. As the largest member......

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