Integrated analysis of single-cell and bulk RNA sequencing data reveals a pan-cancer stemness signature predicting immunotherapy response

Zhang, Z; Wang, ZX; Chen, YX; Wu, HX; Yin, L; Zhao, Q; Luo, HY; Zeng, ZL; Qiu, MZ; Xu, RH

Qiu, MZ; Xu, RH (通讯作者)，Sun Yat Sen Univ, Canc Ctr, Collaborat Innovat Ctr Canc Med, Dept Med Oncol,State Key Lab Oncol South China, Guangzhou 510060, Peoples R China.;Qiu, MZ; Xu, RH (通讯作者)，Chinese Acad Med Sci, Res Unit Precis Diag & Treatment Gastrointestinal, Guangzhou 510060, Peoples R China.;Xu, RH (通讯作者)，Sun Yat Sen Univ, Lab Artificial Intelligence & Data Sci, Canc Ctr, Guangzhou 510060, Peoples R China.

GENOME MEDICINE, 2022; 14 (1):

Abstract

Background Although immune checkpoint inhibitor (ICI) is regarded as a breakthrough in cancer therapy, only a limited fraction of patients benefit fro......

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