Assessment of sigma-1 receptor occupancy in mice with non-radiolabelled FTC-146 as a tracer

Bhyrapuneni, G; Thentu, JB; Mohammed, AR; Aleti, RR; Padala, NP; Ajjala, DR; Nirogi, R

Nirogi, R (reprint author), Suven Life Sci Ltd, Rd 5,Ave 7,Banjara Hills, Hyderabad 500034, India.

JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 2018; 38 (4): 290

Abstract

The use of liquid chromatography coupled with mass spectrometry (LC-MS/MS) is advantageous in in-vivo receptor occupancy assays at pre-clinical drug d......

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