Application of biorelevant in vitro assays for the assessment and optimization of ASD-based formulations for pediatric patients

Niessen, J; Mármol, AL; Ismail, R; Schiele, JT; Rau, K; Wahl, A; Sauer, K; Heinzerling, O; Breitkreutz, J; Koziolek, M

Koziolek, M (通讯作者)，Abbvie Deutschland GmbH & Co KG, Small Mol CMC Dev, Knollstr, Ludwigshafen, Germany.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 185 (): 13

Abstract

Amorphous solid dispersions (ASD) have been a successful formulation strategy to overcome the poor aqueous solubility of many novel drugs, but the dev......

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