Construction of Peptide-Isoquinolone Conjugates via Rh(III)- Catalyzed C-H Activation/Annulation

Song, LL; Lv, ZW; Li, Y; Zhang, K; Van der Eycken, EV; Cai, LC

Song, LL; Cai, LC (通讯作者)，Nanjing Forestry Univ, Jiangsu Coinnovat Ctr Efficient Proc & Utilizat Fo, Jiangsu Prov Key Lab Chem & Utilizat Agroforest Bi, Jiangsu Key Lab Biomass Based Green Fuels & Chem,C, Nanjing 210037, Peoples R China.;Van der Eycken, EV (通讯作者)，Katholieke Univ Leuven, Dept Chem, Lab Organ & Microwave Assisted Chem LOMAC, B-3001 Leuven, Belgium.;Van der Eycken, EV (通讯作者)，Peoples Friendship Univ Russia, RUDN Univ, Moscow 117198, Russia.

ORGANIC LETTERS, 2023; 25 (17): 2996

Abstract

Herein, we disclose a Rh(III)-catalyzed C-H activation/annulation reaction for the derivatization of Lys-based peptides, in situ affording diverse pep......

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